Phylogenetic landscape of Monkeypox Virus (MPV) during the early outbreak in New York City, 2022Article Published on 2023-12-012023-06-09 Journal: Emerging Microbes & Infections [Category] Fulltext, 원숭이두창, [키워드] Cell culture Genome sequencing Monkeypox virus mutations. Orthologous Poxvirus Genes (OPG) Phylogenetic analysis [DOI] 10.1080/22221751.2023.2192830 PMC 바로가기
SARS-CoV-2 CD8+ T cell killing assays using replicating viruses and transgenic antigensArticle Published on 2022-12-162023-07-10 Journal: STAR protocols [Category] COVID19(2023년), [키워드] Cell Biology Cell culture Cell-based Assays CRISPR immunology. [DOI] 10.1016/j.xpro.2022.101699 PMC 바로가기
Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cellsArticle Published on 2022-12-162023-07-11 Journal: STAR protocols [Category] COVID19(2023년), [키워드] Cell culture cell differentiation Microbiology Microscopy organoids stem cells. [DOI] 10.1016/j.xpro.2022.101872 PMC 바로가기
The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineageArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] approach Cell culture circulating comparable contribute COVID-19 determine experimental animal models fitness. G496S genetics monoclonal antibodies omicron Omicron BA.1 Omicron BA.2 pathogenicity phenotype predominant receptor-binding motif Replication SARS-CoV-2 SARS-CoV-2 variant sensitivity spike mutation therapeutic trajectory [DOI] 10.1080/22221751.2022.2111977 PMC 바로가기
3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseasesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 신약개발, 진단, 치료제, [키워드] animal model animal models Antiviral Cell Cell culture comparable consequence Drug repurposing drug target early phase Ex vivo ex vivo infection Ex vivo infection model Health Host human lung IAV in vitro Infection Inflammatory cytokine Influenza influenza A virus Influenza virus Innate immunity innate immunity. interferon interferon response Intervention introduced lung tissue morbidity and mortality murine outbreak pathophysiological pharmacological platform Respiratory disease respiratory viruses responses SARS-CoV-2 therapy tissue Treatment viral infection viral life cycle viral replication virus virus while [DOI] 10.1080/22221751.2022.2117101 PMC 바로가기
Vitamin D and interferon-γ co-operate to increase the ACE-2 receptor expression in primary cultures of human thyroid cellsArticle Published on 2022-11-012022-11-15 Journal: Journal of Endocrinological Investigation [Category] COVID19(2023년), SARS, 진단, [키워드] ACE-2 ACE-2 receptor angiotensin Cell Cell culture cell membrane cells chain Combination combination treatment Course COVID-19 defend demonstrated experiment expressed expression Host IFN-γ immune defense immunocytochemistry in vitro data interferon-γ material membrane mRNA mRNA level observation primary culture Protein protein level reaction receptor RT-PCR SARS-CoV-2 shown supported Therapeutic benefit Thyrocytes Thyroid Thyroid. tissue treated Treatment up-regulate up-regulated up-regulating Vitamin D were measured would increase [DOI] 10.1007/s40618-022-01857-9 PMC 바로가기
Low Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission by Fomites: A Clinical Observational Study in Highly Infectious Coronavirus Disease 2019 PatientsArticle Published on 2022-11-012022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome addressed baseline carrier Cell culture clinical coronavirus 2 coronavirus disease Coronavirus-2 coughing COVID-19 COVID-19 patient Culture Cycle threshold value evaluate fomite transmission Hospitalized Infectious virus initiated Intensive laboratory parameter occur oropharyngeal swab pandemic Patient polymerase chain positive Quantitative respiratory risk Saliva SARS-CoV-2 SARS-CoV-2 transmission Sequencing single-center stability surface stability. Swab Transmission unlikely Viral load viral ribonucleic acid virus virus transmission [DOI] 10.1093/infdis/jiac170 PMC 바로가기
Concentration of SARS-CoV-2-Infected Cell Culture Supernatants for Detection of Virus-like Particles by Scanning Electron MicroscopyArticle Published on 2022-10-282023-07-10 Journal: Viruses [Category] COVID19(2023년), [키워드] Cell culture diagnostic SARS-CoV-2 scanning electron microscopy virus. [DOI] 10.3390/v14112388 PMC 바로가기
Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteasesSARS-CoV-2 주요 및 뎅기 바이러스 프로테아제에 대한 강력한 벤족사보롤 억제제의 발견Article Published on 2022-10-052022-09-11 Journal: European journal of medicinal chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] antiviral agent Antiviral agents biochemical assay Cell Cell culture class contribute cytotoxicity demonstrated Dengue dengue virus DENV-2 Drug development evaluated had no Health inhibit inhibitor M pro membrane MOST penetration protease Proteases Replication RNA virus RNA viruses SARS-CoV-2 stability synthesis target targets [DOI] 10.1016/j.ejmech.2022.114585 PMC 바로가기 [Article Type] Article
Development of a high-sensitivity and short-duration fluorescence in situ hybridization method for viral mRNA detection in HEK 293T cellsArticle Published on 2022-10-042022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome addition antibody Antigen applied approach Blood caused Cell Cell culture cells Concentration contagious coronavirus Coronavirus disease 2019 COVID-19 development Diagnosis disease DNA virus effective false-negative False-positive results faster Fluorescence in situ hybridization gold standard HEK 293T HEK 293T cell hepatitis A virus HPV Human immunodeficiency virus human papillomavirus IgM and IgG IMPROVE influenza viruses limitation MERS-CoV Middle East Monkeypox mRNA mRNA. patients plasmids probe Protein public health reduced respiratory syndrome coronavirus RNA RNA virus RNA virus RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 viral Sensitivity and specificity significantly spike Surveillance tissue Treatment virus was increased yielding [DOI] 10.3389/fcimb.2022.960938 PMC 바로가기